Multi-omics Service for Human/Animal Viruses

Multi-omics Service for Human/Animal Viruses

Viruses are one of the major pathogens that cause diseases in animals, and along with changes in various environmental, ecological, and human behavioral factors, new zoonotic diseases are increasing year by year, and they greatly threaten the health and lives of humans and animals and bring harm and disaster to the healthy development of animal husbandry and agriculture as well as the balance of the natural ecological chain. However, the etiology of many emerging zoonotic diseases is often initially unknown, and there is a lack of systematic understanding of the infectivity of viruses, infection pathways, infection mechanisms, host immune responses to viral infections, and mechanisms by which viruses evade host immunity. For this reason, many new techniques have been applied, and one of the important tools is multi-omics.

Ace Therapeutics provides multi-omics services for human/animal viruses, mainly meta-virome, in addition to other omics such as proteomics.

Multi-Omics Service Options for Human/Animal Viruses


We provide mata-virome sequencing and analysis services for many human/animal viruses. It can help you quickly and accurately identify all the viral compositions in your samples and is important not only in studies of virus discovery, virus traceability, and microbial early warning, but also in studies of virus origin and evolutionary patterns, genetic diversity, and geographic distribution.

Multi-omics Service for Human/Animal Viruses

Extraction Viral particle purification and viral DNA extraction
  • Centrifugation and removal of host cells and debris
  • Filtration and removal of host cells and bacteria
  • Lysis Host cells and bacteria
  • (DNAase) digest the free DNA
  • Extract the viral DNA
Library Meta-virome DNA library construction and sequencing
  • Whole genome amplification
  • Viral DNA fragmentation
  • Library preparation
  • Library quality control
  • Sequencing (illumina platform, PE150 sequencing strategy)
Bioinformatics analysis Raw data processing
  • Raw Data
  • Data quality control
  • Host sequence removal
  • Data assembly
  • Species annotation, functional annotation
Community analysis
  • α diversity analysis
  • β diversity analysis
  • LefSe variance analysis
  • Other statistical analyses
Species and functional analysis
  • Species abundance analysis
  • Differential virus screening
  • Gene prediction
  • Functional Analysis
  • Host prediction analysis
  • Phage host prediction

Sample requirements

  • Stool ≥ 1 g
  • Intestinal contents ≥ 1 g
  • Tissue samples ≥ 2 g
  • Blood samples ≥ 5 mL (blood samples are recommended to send serum)
    Do not repeatedly freeze and thaw during sample preservation, please use dry ice for transport when sending samples.
  • DNA/RNA and other nucleic acid samples ≥ 1 μg, concentration ≥ 50 ng/μL, OD260/280 = 1.8-2.0, ensuring DNA integrity without degradation.
    For this type of sample, subsequent experiments can only be performed after the quality of the sample has been tested and passed.

The multi-omic analysis of human/animal viruses provides new ideas for disease treatment and lays the foundation for studies such as virus surveillance and resistance to existing viral antiviral drugs. For other histology-related questions or multi-omics association analysis, please contact sales or technical support.

Viruses/pathogens in humans/animals for which we can provide multi-omics services include, but are not limited to, those listed below.

Ebola virus
Brucella malta
Brucella porcine
Brucella canis
Yersinia pestis
Burkholderia rhinoceros
Mycobacterium leprae
Francisella tularensis
Ehrlichia canis

Bacillus anthracis
Cryophilus Bacillus
Bacillus spp.
Actinobacillus bovis
Bordetella bronchiseptica
Spirochetes bovis
Campylobacter jejuni
Campylobacter coli
Campylobacter fetus
Neorickettsia glandular

Mycobacterium bovis
Mycobacterium goat
Clostridium difficile
Corynebacterium ulcerans
Escherichia coli
Helicobacter fowl
Helicobacter porcine
Vibrio parahaemolyticus
Pasteurella hemorrhagic, etc.

Mycobacterium vole
Brucella abortus
Salmonella enterica
Salmonella bongolensis
Ewing's ehrlichiosis
Ehrlichia chaffeensis

Note: In addition, there are other services available for you to choose from, please consult us for details.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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