The efficacy evaluation of antiparasitic drugs used in humans, livestock, and pets (dogs, cats, etc.) is a dose confirmation test of parasitic drugs, also known as a phase II clinical trial. Animal tests show their main efficacy, toxicity, and pharmacokinetic properties. The purpose is to further validate the effect of the tested drug on the prevention and treatment of the target indication and the dosing regimen, to determine the clinical effect of the tested drug on the target indication, to observe the adverse effects of the tested drug, and to formulate control measures.
Relying on our integrated parasite biology service technology platform, Ace Therapeutics provides clients with efficacy evaluation analysis services for anti-parasitic drugs worldwide. Based on the results of animal tests, we recommend clinical trial indications, calculate safe doses for human/animal tests, and provide a basis for drug policy formulation, drug selection, and drug development.
Note: We have a variety of efficacy evaluation models for different systems, please consult us for details.
Experimental design |
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Observation indicators | We observed and recorded in detail the physiological status, clinical symptoms, and the occurrence, development, disappearance, and regression of symptoms of the test animals before the test started, after the test started, during the drug administration, and after the drug was stopped. We also tested the necessary routine blood indicators, biochemical indicators, and other relevant indicators according to the experimental design, and used quantitative indicators to assess the efficacy of the drug. |
Statistical analysis | We will select the appropriate statistical analysis procedures to analyze the data. We compare the test drug group with the drug control group for significance and confirm the therapeutic effect of the test drug and its dose. Determine the clinical efficacy of the tested drug on the cases, observe and record the adverse effects of the drug, propose precautions for clinical application of the drug, etc. |
Evaluation of results | We will evaluate the efficacy of the drug in an impartial and scientific manner and produce a trial report, which will include the following:
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Note: For more parasitic drug efficacy evaluation projects, please consult us for details.